miRCURY LNA miRNA Inhibitors and Power Inhibitors are exceptionally potent, enabling assessment of cellular phenotypes in miRNA loss-of-function studies, even in difficult-to-transfect cell lines. miRCURY LNA miRNA Inhibitor Controls and Power Inhibitor Controls are similar in sequence length and LNA design to the inhibitors and have no homology to any known mouse, rat or human miRNA or mRNA sequence.